AK4P3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of AK4P3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AK4P3 at tissue level.

III. Associated gene sets

GO_0046039Biological processGTP metabolic process
GO_0046940Biological processnucleoside monophosphate phosphorylation
GO_0046033Biological processAMP metabolic process
GO_0006172Biological processADP biosynthetic process
GO_0046034Biological processATP metabolic process
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0004017Molecular functionadenylate kinase activity
GO_0005525Molecular functionGTP binding
GO_0046899Molecular functionnucleoside triphosphate adenylate kinase activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameAK4P3
Protein nameAdenylate kinase 4, mitochondrial (AK 4) (EC 2.7.4.10) (EC 2.7.4.6) (Adenylate kinase 3-like) (GTP:AMP phosphotransferase AK4)
SynonymsAK3L1
AK4
DescriptionFUNCTION: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. .

AccessionsA0A8I5KW96
ENST00000418260.3