AGMAT | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell of proximal tubule	4 studies	34% ± 6%	Explore
epithelial cell	3 studies	25% ± 8%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of AGMAT at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	2636.80	226 / 226	96%	60.68	389 / 406
kidney	100%	6007.16	89 / 89	74%	30.14	671 / 901
intestine	61%	405.74	588 / 966	96%	41.87	507 / 527
stomach	53%	44.62	191 / 359	95%	39.18	271 / 286
bladder	57%	30.19	12 / 21	61%	14.59	306 / 504
pancreas	76%	39.42	249 / 328	41%	4.53	73 / 178
prostate	71%	36.89	174 / 245	37%	3.43	187 / 502
adrenal gland	99%	127.52	255 / 258	7%	0.67	15 / 230
lymph node	0%	0	0 / 0	100%	17.84	29 / 29
muscle	100%	775.67	801 / 803	0%	0	0 / 0
spleen	99%	149.17	239 / 241	0%	0	0 / 0
esophagus	35%	21.78	505 / 1445	56%	12.57	102 / 183
peripheral blood	83%	151.99	770 / 929	0%	0	0 / 0
uterus	41%	20.34	70 / 170	42%	4.37	191 / 459
thymus	70%	33.38	459 / 653	12%	1.24	75 / 605
brain	69%	67.88	1814 / 2642	4%	0.29	26 / 705
lung	21%	8.32	123 / 578	32%	5.05	372 / 1155
breast	37%	15.25	168 / 459	16%	1.24	181 / 1118
skin	35%	33.02	628 / 1809	15%	1.36	73 / 472
ovary	11%	4.12	20 / 180	31%	2.72	135 / 430
tonsil	0%	0	0 / 0	42%	3.59	19 / 45
adipose	20%	8.51	241 / 1204	0%	0	0 / 0
blood vessel	6%	2.50	75 / 1335	0%	0	0 / 0
heart	3%	0.94	27 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0000050	Biological process	urea cycle
GO_0033389	Biological process	putrescine biosynthetic process from arginine, using agmatinase
GO_0097055	Biological process	agmatine biosynthetic process
GO_0005739	Cellular component	mitochondrion
GO_0047972	Molecular function	guanidinopropionase activity
GO_0047971	Molecular function	guanidinobutyrase activity
GO_0046872	Molecular function	metal ion binding
GO_0008783	Molecular function	agmatinase activity
GO_0004053	Molecular function	arginase activity

Gene name	AGMAT
Protein name	Guanidino acid hydrolase, mitochondrial (EC 3.5.3.-) (Arginase, mitochondrial) (EC 3.5.3.1) (Guanidinobutyrase, mitochondrial) (EC 3.5.3.7) (Guanidinopropionase, mitochondrial) (EC 3.5.3.17)
Synonyms	GDAH
Description	FUNCTION: Hydrolyzes linear guanidino acids to form urea and the corresponding amines. Displays specificity for substrates having a negatively charged head group and short chains including taurocyamine, guanidino propanoic and butanoic acids. May protect cells by detoxifying potentially harmful amounts of guanidino acids. Metabolizes L-arginine with low efficiency. .
Accessions	Q9BSE5 ENST00000375826.4

AGMAT report