ADSS1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ADSS1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADSS1 at tissue level.

III. Associated gene sets

GO_0002376Biological processimmune system process
GO_0071466Biological processcellular response to xenobiotic stimulus
GO_0044208Biological process'de novo' AMP biosynthetic process
GO_0006541Biological processglutamine metabolic process
GO_0014850Biological processresponse to muscle activity
GO_0006167Biological processAMP biosynthetic process
GO_0042594Biological processresponse to starvation
GO_0006531Biological processaspartate metabolic process
GO_0071257Biological processcellular response to electrical stimulus
GO_0046040Biological processIMP metabolic process
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0051015Molecular functionactin filament binding
GO_0042802Molecular functionidentical protein binding
GO_0000287Molecular functionmagnesium ion binding
GO_0005525Molecular functionGTP binding
GO_0042301Molecular functionphosphate ion binding
GO_0004019Molecular functionadenylosuccinate synthase activity
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameADSS1
Protein nameAdenylosuccinate synthetase isozyme 1 (AMPSase 1) (AdSS 1) (EC 6.3.4.4) (Adenylosuccinate synthetase, basic isozyme) (Adenylosuccinate synthetase, muscle isozyme) (M-type adenylosuccinate synthetase) (Adenylosuccinate synthetase-like 1) (AdSSL1) (IMP--aspartate ligase 1)
Adenylosuccinate synthase 1
SynonymsADSSL1
DescriptionFUNCTION: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. .

AccessionsG3V5D8
ENST00000553540.5
ENST00000330877.7 [Q8N142-1]
ENST00000555674.1
ENST00000710323.1 [Q8N142-1]
Q8N142
ENST00000332972.9 [Q8N142-2]
ENST00000556623.1
G3V2N1
G3V232