ADPRM report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ADPRM at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADPRM at tissue level.

III. Associated gene sets

GO_0005829Cellular componentcytosol
GO_0030145Molecular functionmanganese ion binding
GO_0047631Molecular functionADP-ribose diphosphatase activity
GO_0008663Molecular function2',3'-cyclic-nucleotide 2'-phosphodiesterase activity
GO_0047734Molecular functionCDP-glycerol diphosphatase activity

IV. Literature review

[source]
Gene nameADPRM
Protein nameManganese-dependent ADP-ribose/CDP-alcohol diphosphatase (EC 3.6.1.13) (EC 3.6.1.16) (EC 3.6.1.53) (ADPRibase-Mn) (CDP-choline phosphohydrolase)
ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
SynonymsMDS006
Nbla03831
C17orf48
DescriptionFUNCTION: Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity). .

AccessionsQ3LIE5
V9GYR6
ENST00000379774.5 [Q3LIE5-1]
W0NWJ0
ENST00000609540.1
ENST00000468843.1 [Q3LIE5-3]