ADM2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ADM2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADM2 at tissue level.

III. Associated gene sets

GO_0007631Biological processfeeding behavior
GO_0010628Biological processpositive regulation of gene expression
GO_0001525Biological processangiogenesis
GO_0003073Biological processregulation of systemic arterial blood pressure
GO_0006468Biological processprotein phosphorylation
GO_0045776Biological processnegative regulation of blood pressure
GO_0010460Biological processpositive regulation of heart rate
GO_0045766Biological processpositive regulation of angiogenesis
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0005576Cellular componentextracellular region
GO_0044877Molecular functionprotein-containing complex binding
GO_0005179Molecular functionhormone activity

IV. Literature review

[source]
Gene nameADM2
Protein nameProtein ADM2 (Intermedin) [Cleaved into: Adrenomedullin-2 (AM2) (Intermedin-long) (IMDL); Intermedin-short (IMDS)]
SynonymsAM2
DescriptionFUNCTION: [Adrenomedullin-2]: May play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway. .; FUNCTION: [Intermedin-short]: May play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway. .

AccessionsENST00000395737.2
Q7Z4H4
ENST00000395738.2