ADH1B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001523Biological processretinoid metabolic process
GO_0042573Biological processretinoic acid metabolic process
GO_0042572Biological processretinol metabolic process
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0004024Molecular functionalcohol dehydrogenase (NAD+) activity, zinc-dependent
GO_0004022Molecular functionalcohol dehydrogenase (NAD+) activity
GO_0004745Molecular functionall-trans-retinol dehydrogenase (NAD+) activity
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameADH1B
Protein nameAll-trans-retinol dehydrogenase [NAD(+)] ADH1B
All-trans-retinol dehydrogenase [NAD(+)] ADH1B (EC 1.1.1.105) (Alcohol dehydrogenase 1B) (Alcohol dehydrogenase subunit beta)
SynonymsADH2
DescriptionFUNCTION: Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate in retinoid metabolism . In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal . Catalyzes in the oxidative direction with higher efficiency . Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal . .

AccessionsP00325
D6RHZ6
ENST00000506651.5 [P00325-2]
ENST00000625860
ENST00000506651
ENST00000305046.13 [P00325-1]
ENST00000625860.2 [P00325-2]