I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 25% ± 1% | |
| glutamatergic neuron | 3 studies | 29% ± 5% | |
| oligodendrocyte | 3 studies | 22% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 25% ± 1% | |
| glutamatergic neuron | 3 studies | 29% ± 5% | |
| oligodendrocyte | 3 studies | 22% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 25% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 625.07 | 1445 / 1445 | 100% | 6.77 | 183 / 183 |
| brain | 100% | 733.41 | 2637 / 2642 | 100% | 11.00 | 705 / 705 |
| prostate | 100% | 837.20 | 245 / 245 | 100% | 8.64 | 500 / 502 |
| skin | 100% | 611.54 | 1809 / 1809 | 100% | 10.13 | 470 / 472 |
| thymus | 100% | 853.28 | 653 / 653 | 100% | 7.84 | 602 / 605 |
| intestine | 100% | 787.84 | 966 / 966 | 99% | 8.23 | 524 / 527 |
| uterus | 100% | 610.65 | 170 / 170 | 99% | 6.37 | 455 / 459 |
| stomach | 100% | 604.21 | 359 / 359 | 99% | 7.45 | 283 / 286 |
| pancreas | 100% | 491.89 | 328 / 328 | 99% | 5.92 | 176 / 178 |
| breast | 100% | 576.80 | 459 / 459 | 99% | 6.39 | 1104 / 1118 |
| bladder | 100% | 626.29 | 21 / 21 | 98% | 6.74 | 496 / 504 |
| adrenal gland | 100% | 930.27 | 258 / 258 | 97% | 7.23 | 224 / 230 |
| lung | 99% | 561.50 | 574 / 578 | 98% | 6.05 | 1132 / 1155 |
| ovary | 100% | 612.95 | 180 / 180 | 97% | 5.99 | 418 / 430 |
| liver | 100% | 563.65 | 226 / 226 | 96% | 4.55 | 390 / 406 |
| kidney | 100% | 718.30 | 89 / 89 | 92% | 4.48 | 833 / 901 |
| eye | 0% | 0 | 0 / 0 | 100% | 17.27 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 7.60 | 29 / 29 |
| spleen | 100% | 924.11 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.60 | 1 / 1 |
| adipose | 100% | 536.10 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 99% | 731.42 | 797 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 98% | 373.65 | 1312 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 704.84 | 844 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 5.97 | 44 / 45 |
| peripheral blood | 88% | 295.00 | 821 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0055088 | Biological process | lipid homeostasis |
| GO_0007005 | Biological process | mitochondrion organization |
| GO_1903852 | Biological process | positive regulation of cristae formation |
| GO_0010637 | Biological process | negative regulation of mitochondrial fusion |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | ADCK1 |
| Protein name | AarF domain-containing protein kinase 1 (EC 2.7.-.-) AarF domain-containing protein kinase 1 AarF domain containing kinase 1 |
| Synonyms | |
| Description | FUNCTION: Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase-independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT . The action of this enzyme is not yet clear (Probable). It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable). . |
| Accessions | ENST00000238561.10 [Q86TW2-2] G3V3J2 ENST00000556048.5 ENST00000393639.8 Q86TW2 F8W9Q8 ENST00000341211.5 [Q86TW2-3] G3V426 ENST00000557501.5 |
