ADAMTS14 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ADAMTS14 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADAMTS14 at tissue level.

III. Associated gene sets

GO_0030199Biological processcollagen fibril organization
GO_0030198Biological processextracellular matrix organization
GO_0006508Biological processproteolysis
GO_0030574Biological processcollagen catabolic process
GO_0005576Cellular componentextracellular region
GO_0031012Cellular componentextracellular matrix
GO_0004222Molecular functionmetalloendopeptidase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameADAMTS14
Protein nameA disintegrin and metalloproteinase with thrombospondin motifs 14 (ADAM-TS 14) (ADAM-TS14) (ADAMTS-14) (EC 3.4.24.-)
Synonyms
DescriptionFUNCTION: Has aminoprocollagen type I processing activity in the absence of ADAMTS2 . Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity . Cleaves lysyl oxidase LOX at a site downstream of its propeptide cleavage site to produce a short LOX form . .

AccessionsQ8WXS8
ENST00000373207.2 [Q8WXS8-1]
ENST00000373208.5 [Q8WXS8-4]