I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 4 studies | 25% ± 6% | |
| retinal cone cell | 3 studies | 36% ± 9% | |
| GABAergic neuron | 3 studies | 32% ± 7% | |
| glutamatergic neuron | 3 studies | 38% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 4 studies | 25% ± 6% | |
| retinal cone cell | 3 studies | 36% ± 9% | |
| GABAergic neuron | 3 studies | 32% ± 7% | |
| glutamatergic neuron | 3 studies | 38% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 26% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 541.39 | 245 / 245 | 100% | 6.00 | 502 / 502 |
| brain | 100% | 673.25 | 2636 / 2642 | 100% | 8.57 | 705 / 705 |
| thymus | 100% | 831.00 | 653 / 653 | 100% | 6.89 | 603 / 605 |
| kidney | 100% | 728.54 | 89 / 89 | 100% | 5.60 | 898 / 901 |
| breast | 100% | 469.43 | 458 / 459 | 100% | 6.32 | 1113 / 1118 |
| uterus | 100% | 416.94 | 170 / 170 | 99% | 5.31 | 455 / 459 |
| esophagus | 100% | 516.32 | 1441 / 1445 | 99% | 4.12 | 181 / 183 |
| adrenal gland | 100% | 613.47 | 258 / 258 | 98% | 4.87 | 226 / 230 |
| ovary | 99% | 393.25 | 178 / 180 | 99% | 3.97 | 427 / 430 |
| lung | 97% | 362.24 | 559 / 578 | 99% | 4.32 | 1140 / 1155 |
| bladder | 100% | 520.71 | 21 / 21 | 95% | 3.49 | 479 / 504 |
| liver | 99% | 406.91 | 224 / 226 | 96% | 3.67 | 389 / 406 |
| skin | 96% | 429.38 | 1743 / 1809 | 98% | 8.20 | 464 / 472 |
| pancreas | 95% | 227.90 | 313 / 328 | 99% | 3.29 | 176 / 178 |
| stomach | 99% | 364.11 | 356 / 359 | 94% | 3.07 | 270 / 286 |
| intestine | 100% | 548.54 | 966 / 966 | 92% | 2.84 | 485 / 527 |
| spleen | 100% | 385.70 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 4.91 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.38 | 1 / 1 |
| muscle | 100% | 1170.34 | 802 / 803 | 0% | 0 | 0 / 0 |
| adipose | 100% | 466.38 | 1201 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 436.59 | 1328 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 6.90 | 79 / 80 |
| heart | 98% | 1116.70 | 840 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 3.35 | 28 / 29 |
| peripheral blood | 32% | 227.17 | 294 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0046103 | Biological process | inosine biosynthetic process |
| GO_0006154 | Biological process | adenosine catabolic process |
| GO_0009117 | Biological process | nucleotide metabolic process |
| GO_0005829 | Cellular component | cytosol |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0062154 | Molecular function | N6-methyl-AMP deaminase activity |
| GO_0004000 | Molecular function | adenosine deaminase activity |
| Gene name | ADAL |
| Protein name | Adenosine deaminase-like protein (EC 3.5.4.-) (Adenosine deaminase-like protein isoform 1) (N6-mAMP deaminase) (HsMAPDA) (N6-methyl-AMP aminohydrolase) Adenosine deaminase like |
| Synonyms | ADAL1 |
| Description | FUNCTION: Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine . Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A) . Catalyzes the removal of different alkyl groups not only from N6-substituted purine or 2-aminopurine nucleoside monophosphates but also from O6-substituted compounds in vitro . . |
| Accessions | ENST00000610420.4 [Q6DHV7-2] ENST00000563551.1 ENST00000428046.7 [Q6DHV7-3] ENST00000566154.1 Q6DHV7 ENST00000562188.7 [Q6DHV7-1] ENST00000422466.6 [Q6DHV7-3] H3BUD6 H3BQR9 ENST00000389651.8 [Q6DHV7-2] |
