Insufficient scRNA-seq data for expression of ACSM4 at single-cell level.
Insufficient scRNA-seq data for expression of ACSM4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 95% | 6.02 | 434 / 459 | 12% | 0.27 | 129 / 1118 |
| lung | 91% | 4.39 | 526 / 578 | 7% | 0.13 | 77 / 1155 |
| spleen | 97% | 13.62 | 233 / 241 | 0% | 0 | 0 / 0 |
| adipose | 94% | 6.04 | 1131 / 1204 | 0% | 0 | 0 / 0 |
| intestine | 87% | 3.39 | 843 / 966 | 2% | 0.03 | 9 / 527 |
| adrenal gland | 67% | 1.69 | 172 / 258 | 22% | 0.39 | 50 / 230 |
| skin | 78% | 2.79 | 1405 / 1809 | 3% | 0.07 | 14 / 472 |
| esophagus | 71% | 1.83 | 1032 / 1445 | 4% | 0.08 | 8 / 183 |
| bladder | 71% | 2.14 | 15 / 21 | 4% | 0.08 | 18 / 504 |
| thymus | 73% | 1.85 | 479 / 653 | 0% | 0 | 0 / 605 |
| blood vessel | 73% | 2.18 | 979 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 63% | 1.46 | 226 / 359 | 6% | 0.09 | 16 / 286 |
| heart | 67% | 1.51 | 580 / 861 | 0% | 0 | 0 / 0 |
| brain | 63% | 1.57 | 1668 / 2642 | 2% | 0.03 | 14 / 705 |
| peripheral blood | 65% | 3.52 | 603 / 929 | 0% | 0 | 0 / 0 |
| uterus | 63% | 1.36 | 107 / 170 | 1% | 0.03 | 4 / 459 |
| muscle | 63% | 1.48 | 506 / 803 | 0% | 0 | 0 / 0 |
| kidney | 56% | 1.02 | 50 / 89 | 4% | 0.08 | 39 / 901 |
| prostate | 55% | 1.24 | 135 / 245 | 1% | 0.01 | 4 / 502 |
| ovary | 54% | 1.04 | 98 / 180 | 1% | 0.01 | 3 / 430 |
| liver | 54% | 1.01 | 121 / 226 | 0% | 0.01 | 2 / 406 |
| pancreas | 34% | 0.57 | 111 / 328 | 3% | 0.06 | 5 / 178 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006633 | Biological process | fatty acid biosynthetic process |
| GO_0006637 | Biological process | acyl-CoA metabolic process |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0015645 | Molecular function | fatty acid ligase activity |
| GO_0004321 | Molecular function | fatty-acyl-CoA synthase activity |
| GO_0031956 | Molecular function | medium-chain fatty acid-CoA ligase activity |
| GO_0102391 | Molecular function | decanoate-CoA ligase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | ACSM4 |
| Protein name | Acyl-coenzyme A synthetase ACSM4, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 4) |
| Synonyms | |
| Description | FUNCTION: Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (By similarity). Capable of activating medium-chain fatty acids with a preference for C6-12 fatty acids (By similarity). . |
| Accessions | ENST00000399422.5 P0C7M7 |