ACSM3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ACSM3 at tissue level.

III. Associated gene sets

GO_0008217Biological processregulation of blood pressure
GO_0042632Biological processcholesterol homeostasis
GO_0006633Biological processfatty acid biosynthetic process
GO_0006637Biological processacyl-CoA metabolic process
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0015645Molecular functionfatty acid ligase activity
GO_0004321Molecular functionfatty-acyl-CoA synthase activity
GO_0031956Molecular functionmedium-chain fatty acid-CoA ligase activity
GO_0043759Molecular function2-methylbutanoate-CoA ligase activity
GO_0050218Molecular functionpropionate-CoA ligase activity
GO_0018729Molecular functionpropionate CoA-transferase activity
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameACSM3
Protein namemedium-chain acyl-CoA ligase (EC 6.2.1.2)
Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Propionate--CoA ligase) (EC 6.2.1.17) (Protein SA homolog)
Acyl-CoA synthetase medium chain family member 3
SynonymsSAH
DescriptionFUNCTION: Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism . Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms (By similarity). .

AccessionsH3BV29
H3BR33
ENST00000568235.5
ENST00000563914.1
ENST00000562251.5
ENST00000289416.10 [Q53FZ2-1]
H3BVD5
H3BT38
Q53FZ2
ENST00000564701.1
ENST00000561795.5
H3BTG0
ENST00000569141.1
ENST00000440284.6 [Q53FZ2-2]
ENST00000561584.5
H3BSM0
H3BUF2