ACSM2A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0070328Biological processtriglyceride homeostasis
GO_0006633Biological processfatty acid biosynthetic process
GO_0006637Biological processacyl-CoA metabolic process
GO_0036112Biological processmedium-chain fatty-acyl-CoA metabolic process
GO_0042593Biological processglucose homeostasis
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0015645Molecular functionfatty acid ligase activity
GO_0004321Molecular functionfatty-acyl-CoA synthase activity
GO_0031956Molecular functionmedium-chain fatty acid-CoA ligase activity
GO_0102391Molecular functiondecanoate-CoA ligase activity
GO_0018858Molecular functionbenzoate-CoA ligase activity
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameACSM2A
Protein nameAcyl-CoA synthetase medium chain family member 2A
Acyl-coenzyme A synthetase ACSM2A, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 2A) (Benzoate--CoA ligase) (EC 6.2.1.25) (Butyrate--CoA ligase 2A) (Butyryl-coenzyme A synthetase 2A) (Middle-chain acyl-CoA synthetase 2A)
medium-chain acyl-CoA ligase (EC 6.2.1.2)
SynonymsACSM2
MACS2
DescriptionFUNCTION: Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (By similarity). Capable of activating medium-chain fatty acids (e.g. butyric (C4) to decanoic (C10) acids), and certain carboxylate-containing xenobiotics, e.g. benzoate (By similarity). .

AccessionsENST00000219054.10
ENST00000576361.5
ENST00000574692.5
ENST00000574251.5
ENST00000575690.5
E7EPS5
ENST00000571894.1
I3L2Y5
ENST00000417235.6
ENST00000573854.6
ENST00000396104.2
F5GWL3
I3L339
I3L438
Q08AH3