ACOT4 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of ACOT4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	695.45	226 / 226	97%	13.90	394 / 406
breast	100%	312.09	457 / 459	97%	21.59	1086 / 1118
kidney	100%	511.44	89 / 89	89%	10.53	804 / 901
bladder	100%	74.81	21 / 21	88%	7.28	445 / 504
pancreas	94%	96.19	307 / 328	94%	6.59	167 / 178
thymus	91%	74.82	596 / 653	91%	4.50	551 / 605
intestine	93%	107.42	902 / 966	87%	5.43	458 / 527
lung	92%	132.35	533 / 578	86%	6.37	994 / 1155
prostate	96%	90.47	234 / 245	81%	3.35	405 / 502
uterus	86%	54.83	146 / 170	89%	7.97	409 / 459
esophagus	90%	83.69	1300 / 1445	79%	4.56	145 / 183
stomach	82%	60.24	296 / 359	86%	5.14	247 / 286
ovary	70%	41.26	126 / 180	89%	7.17	383 / 430
skin	71%	54.17	1283 / 1809	65%	3.94	305 / 472
brain	97%	176.47	2563 / 2642	32%	1.20	228 / 705
adrenal gland	98%	155.67	253 / 258	27%	1.22	62 / 230
lymph node	0%	0	0 / 0	100%	8.02	29 / 29
ureter	0%	0	0 / 0	100%	7.50	1 / 1
adipose	99%	272.55	1197 / 1204	0%	0	0 / 0
spleen	98%	101.65	236 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	91%	6.55	41 / 45
heart	78%	52.07	675 / 861	0%	0	0 / 0
blood vessel	76%	53.32	1014 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	74%	3.60	59 / 80
peripheral blood	44%	55.02	413 / 929	0%	0	0 / 0
muscle	44%	20.36	353 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0043648	Biological process	dicarboxylic acid metabolic process
GO_0032789	Biological process	unsaturated monocarboxylic acid metabolic process
GO_0006633	Biological process	fatty acid biosynthetic process
GO_0043649	Biological process	dicarboxylic acid catabolic process
GO_0019605	Biological process	butyrate metabolic process
GO_0000038	Biological process	very long-chain fatty acid metabolic process
GO_0001676	Biological process	long-chain fatty acid metabolic process
GO_0006631	Biological process	fatty acid metabolic process
GO_0006637	Biological process	acyl-CoA metabolic process
GO_0032788	Biological process	saturated monocarboxylic acid metabolic process
GO_0006104	Biological process	succinyl-CoA metabolic process
GO_0046459	Biological process	short-chain fatty acid metabolic process
GO_0005829	Cellular component	cytosol
GO_0005777	Cellular component	peroxisome
GO_0005782	Cellular component	peroxisomal matrix
GO_0047617	Molecular function	fatty acyl-CoA hydrolase activity
GO_0052689	Molecular function	carboxylic ester hydrolase activity
GO_0004778	Molecular function	succinyl-CoA hydrolase activity

Gene name	ACOT4
Protein name	Peroxisomal succinyl-coenzyme A thioesterase (EC 3.1.2.3) (Acyl-coenzyme A thioesterase 4) (Acyl-CoA thioesterase 4) (EC 3.1.2.2) (PTE-2b) (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-CoA thioesterase Ib) (PTE-Ib)
Synonyms	PTE2B PTEIB
Description	FUNCTION: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels . Functions as a peroxisomal succinyl-coenzyme A thioesterase that can also hydrolyze glutaryl-CoA and long chain saturated acyl-CoAs . .
Accessions	Q8N9L9 ENST00000326303.5

ACOT4 report