ACOT1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ACOT1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ACOT1 at tissue level.

III. Associated gene sets

GO_0000038Biological processvery long-chain fatty acid metabolic process
GO_0001676Biological processlong-chain fatty acid metabolic process
GO_0006631Biological processfatty acid metabolic process
GO_0006637Biological processacyl-CoA metabolic process
GO_0005829Cellular componentcytosol
GO_0047617Molecular functionfatty acyl-CoA hydrolase activity
GO_0052689Molecular functioncarboxylic ester hydrolase activity

IV. Literature review

[source]
Gene nameACOT1
Protein nameAcyl-CoA thioesterase 1
Acyl-coenzyme A thioesterase 1 (Acyl-CoA thioesterase 1) (EC 3.1.2.-) (CTE-I) (CTE-Ib) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase) (Palmitoyl-coenzyme A thioesterase) (EC 3.1.2.2)
SynonymsCTE1
DescriptionFUNCTION: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. More active towards saturated and unsaturated long chain fatty acyl-CoAs (C12-C20). .

AccessionsQ86TX2
ENST00000557556.1
G3V4F2
ENST00000311148.9
A1L172