ACADS report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006635Biological processfatty acid beta-oxidation
GO_0046359Biological processbutyrate catabolic process
GO_0033539Biological processfatty acid beta-oxidation using acyl-CoA dehydrogenase
GO_0005813Cellular componentcentrosome
GO_0005654Cellular componentnucleoplasm
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0005634Cellular componentnucleus
GO_0003995Molecular functionacyl-CoA dehydrogenase activity
GO_0004085Molecular functionbutyryl-CoA dehydrogenase activity
GO_0050660Molecular functionflavin adenine dinucleotide binding

IV. Literature review

[source]
Gene nameACADS
Protein nameShort-chain specific acyl-CoA dehydrogenase, mitochondrial (SCAD) (EC 1.3.8.1) (Butyryl-CoA dehydrogenase)
Short-chain specific acyl-CoA dehydrogenase, mitochondrial (EC 1.3.8.1) (Butyryl-CoA dehydrogenase)
SynonymshCG_27359
DescriptionFUNCTION: Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats (By similarity). The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (By similarity). Among the different mitochondrial acyl-CoA dehydrogenases, short-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 4 to 6 carbons long primary chains . .

AccessionsENST00000411593.2
P16219
E5KSD5
ENST00000242592.9
E9PE82
D4QEZ8