Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 3 studies | 24% ± 0% | |
GABAergic neuron | 3 studies | 20% ± 1% | |
glutamatergic neuron | 3 studies | 31% ± 7% |
Insufficient scRNA-seq data for expression of ACAD8 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 3140.57 | 245 / 245 | 100% | 59.49 | 502 / 502 |
thymus | 100% | 4650.78 | 653 / 653 | 100% | 26.19 | 603 / 605 |
brain | 100% | 1840.76 | 2631 / 2642 | 100% | 26.38 | 705 / 705 |
breast | 100% | 2206.75 | 459 / 459 | 99% | 13.04 | 1110 / 1118 |
kidney | 100% | 2759.33 | 89 / 89 | 99% | 13.21 | 894 / 901 |
bladder | 100% | 1867.00 | 21 / 21 | 99% | 11.34 | 500 / 504 |
pancreas | 100% | 2068.13 | 328 / 328 | 99% | 10.41 | 176 / 178 |
lung | 100% | 2261.82 | 577 / 578 | 99% | 18.18 | 1144 / 1155 |
stomach | 100% | 1871.87 | 359 / 359 | 99% | 8.84 | 282 / 286 |
intestine | 100% | 2065.61 | 966 / 966 | 98% | 10.10 | 517 / 527 |
skin | 100% | 2458.18 | 1809 / 1809 | 98% | 10.85 | 462 / 472 |
uterus | 100% | 2024.73 | 170 / 170 | 97% | 10.56 | 447 / 459 |
liver | 100% | 2184.57 | 226 / 226 | 97% | 9.86 | 395 / 406 |
ovary | 100% | 1764.27 | 180 / 180 | 97% | 9.13 | 418 / 430 |
esophagus | 100% | 1794.34 | 1445 / 1445 | 96% | 7.34 | 175 / 183 |
adrenal gland | 100% | 2618.33 | 258 / 258 | 95% | 13.46 | 219 / 230 |
adipose | 100% | 1811.73 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 11.40 | 29 / 29 |
muscle | 100% | 2337.38 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2412.14 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.24 | 1 / 1 |
blood vessel | 100% | 1416.09 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 1928.57 | 849 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 9.43 | 77 / 80 |
tonsil | 0% | 0 | 0 / 0 | 96% | 7.90 | 43 / 45 |
peripheral blood | 93% | 1092.61 | 867 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006574 | Biological process | valine catabolic process |
GO_0006629 | Biological process | lipid metabolic process |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0003995 | Molecular function | acyl-CoA dehydrogenase activity |
GO_0050660 | Molecular function | flavin adenine dinucleotide binding |
GO_0102035 | Molecular function | 2-methylpropanoyl-CoA dehydrogenase activity |
Gene name | ACAD8 |
Protein name | Acyl-CoA dehydrogenase family member 8 Isobutyryl-CoA dehydrogenase, mitochondrial (IBDH) (EC 1.3.8.5) (Activator-recruited cofactor 42 kDa component) (ARC42) (Acyl-CoA dehydrogenase family member 8) (ACAD-8) Acyl-Coenzyme A dehydrogenase family, member 8, isoform CRA_b (cDNA FLJ43383 fis, clone OCBBF2006058, highly similar to Homo sapiens acyl-Coenzyme A dehydrogenase-8 mRNA) |
Synonyms | ARC42 IBD hCG_37259 |
Description | FUNCTION: Isobutyryl-CoA dehydrogenase which catalyzes the conversion of 2-methylpropanoyl-CoA to (2E)-2-methylpropenoyl-CoA in the valine catabolic pathway . To a lesser extent, also able to catalyze the oxidation of (2S)-2-methylbutanoyl-CoA . . |
Accessions | E9PKP9 E9PLS3 ENST00000524426.5 ENST00000526026.5 ENST00000374752.6 [Q9UKU7-2] Q9UKU7 Q6ZUS0 ENST00000281182.9 [Q9UKU7-1] |