ACAD8 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ACAD8 at tissue level.

III. Associated gene sets

GO_0006574Biological processvaline catabolic process
GO_0006629Biological processlipid metabolic process
GO_0005759Cellular componentmitochondrial matrix
GO_0003995Molecular functionacyl-CoA dehydrogenase activity
GO_0050660Molecular functionflavin adenine dinucleotide binding
GO_0102035Molecular function2-methylpropanoyl-CoA dehydrogenase activity

IV. Literature review

[source]
Gene nameACAD8
Protein nameAcyl-CoA dehydrogenase family member 8
Isobutyryl-CoA dehydrogenase, mitochondrial (IBDH) (EC 1.3.8.5) (Activator-recruited cofactor 42 kDa component) (ARC42) (Acyl-CoA dehydrogenase family member 8) (ACAD-8)
Acyl-Coenzyme A dehydrogenase family, member 8, isoform CRA_b (cDNA FLJ43383 fis, clone OCBBF2006058, highly similar to Homo sapiens acyl-Coenzyme A dehydrogenase-8 mRNA)
SynonymsARC42
IBD
hCG_37259
DescriptionFUNCTION: Isobutyryl-CoA dehydrogenase which catalyzes the conversion of 2-methylpropanoyl-CoA to (2E)-2-methylpropenoyl-CoA in the valine catabolic pathway . To a lesser extent, also able to catalyze the oxidation of (2S)-2-methylbutanoyl-CoA . .

AccessionsE9PKP9
E9PLS3
ENST00000524426.5
ENST00000526026.5
ENST00000374752.6 [Q9UKU7-2]
Q9UKU7
Q6ZUS0
ENST00000281182.9 [Q9UKU7-1]