Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 23 studies | 27% ± 10% | |
microglial cell | 11 studies | 32% ± 12% | |
myeloid cell | 11 studies | 28% ± 9% | |
oligodendrocyte precursor cell | 10 studies | 32% ± 14% | |
oligodendrocyte | 10 studies | 29% ± 11% | |
glutamatergic neuron | 7 studies | 38% ± 23% | |
endothelial cell | 6 studies | 25% ± 6% | |
epithelial cell | 6 studies | 31% ± 11% | |
dendritic cell | 6 studies | 24% ± 5% | |
GABAergic neuron | 6 studies | 39% ± 21% | |
conventional dendritic cell | 5 studies | 25% ± 4% | |
astrocyte | 5 studies | 25% ± 8% | |
monocyte | 4 studies | 22% ± 4% | |
alveolar macrophage | 4 studies | 27% ± 8% | |
interneuron | 4 studies | 39% ± 21% | |
neuron | 4 studies | 41% ± 13% | |
pancreatic A cell | 3 studies | 33% ± 10% | |
mononuclear phagocyte | 3 studies | 31% ± 9% | |
non-classical monocyte | 3 studies | 20% ± 2% | |
abnormal cell | 3 studies | 28% ± 8% | |
basal cell | 3 studies | 27% ± 9% | |
transit amplifying cell | 3 studies | 26% ± 11% | |
connective tissue cell | 3 studies | 18% ± 2% | |
plasmacytoid dendritic cell | 3 studies | 20% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 3112.44 | 258 / 258 | 100% | 60.02 | 230 / 230 |
brain | 100% | 7211.98 | 2642 / 2642 | 100% | 90.61 | 705 / 705 |
ovary | 100% | 2762.82 | 180 / 180 | 100% | 62.04 | 430 / 430 |
pancreas | 100% | 4512.63 | 328 / 328 | 100% | 64.77 | 178 / 178 |
stomach | 100% | 3169.07 | 359 / 359 | 100% | 77.14 | 286 / 286 |
thymus | 100% | 8215.01 | 653 / 653 | 100% | 115.08 | 605 / 605 |
skin | 100% | 4290.49 | 1808 / 1809 | 100% | 88.89 | 472 / 472 |
esophagus | 100% | 2981.60 | 1444 / 1445 | 100% | 49.95 | 183 / 183 |
kidney | 100% | 3467.20 | 89 / 89 | 100% | 61.93 | 900 / 901 |
bladder | 100% | 3538.29 | 21 / 21 | 100% | 98.88 | 503 / 504 |
uterus | 100% | 2523.75 | 170 / 170 | 100% | 69.54 | 458 / 459 |
intestine | 100% | 2808.45 | 966 / 966 | 100% | 72.92 | 525 / 527 |
prostate | 100% | 3387.51 | 245 / 245 | 100% | 106.44 | 500 / 502 |
breast | 100% | 2775.94 | 459 / 459 | 99% | 73.93 | 1112 / 1118 |
lung | 99% | 3064.89 | 575 / 578 | 100% | 59.51 | 1153 / 1155 |
liver | 96% | 1530.98 | 217 / 226 | 100% | 49.59 | 404 / 406 |
eye | 0% | 0 | 0 / 0 | 100% | 85.21 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 58.72 | 29 / 29 |
spleen | 100% | 2148.72 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 63.42 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 185.17 | 1 / 1 |
adipose | 100% | 2717.22 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 2542.09 | 1325 / 1335 | 0% | 0 | 0 / 0 |
heart | 93% | 1704.07 | 798 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 58% | 1144.51 | 540 / 929 | 0% | 0 | 0 / 0 |
muscle | 45% | 480.58 | 359 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0052651 | Biological process | monoacylglycerol catabolic process |
GO_0007628 | Biological process | adult walking behavior |
GO_0098734 | Biological process | macromolecule depalmitoylation |
GO_0010996 | Biological process | response to auditory stimulus |
GO_0050727 | Biological process | regulation of inflammatory response |
GO_0006660 | Biological process | phosphatidylserine catabolic process |
GO_0046464 | Biological process | acylglycerol catabolic process |
GO_0046475 | Biological process | glycerophospholipid catabolic process |
GO_0019369 | Biological process | arachidonic acid metabolic process |
GO_0009395 | Biological process | phospholipid catabolic process |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0032281 | Cellular component | AMPA glutamate receptor complex |
GO_0032839 | Cellular component | dendrite cytoplasm |
GO_0004620 | Molecular function | phospholipase activity |
GO_0004622 | Molecular function | lysophospholipase activity |
GO_0008474 | Molecular function | palmitoyl-(protein) hydrolase activity |
GO_0047372 | Molecular function | acylglycerol lipase activity |
Gene name | ABHD12 |
Protein name | Lysophosphatidylserine lipase ABHD12 (EC 3.1.-.-) (2-arachidonoylglycerol hydrolase ABHD12) (Abhydrolase domain-containing protein 12) (hABHD12) (Monoacylglycerol lipase ABHD12) (EC 3.1.1.23) (Oxidized phosphatidylserine lipase ABHD12) (EC 3.1.-.-) Abhydrolase domain containing 12, lysophospholipase Lysophosphatidylserine lipase ABHD12 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase ABHD12) (Abhydrolase domain-containing protein 12) (Monoacylglycerol lipase ABHD12) (Oxidized phosphatidylserine lipase ABHD12) |
Synonyms | C20orf22 |
Description | FUNCTION: Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes . Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system (By similarity). Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal . Also has monoacylglycerol (MAG) lipase activity: hydrolyzes 2-arachidonoylglycerol (2-AG), thereby acting as a regulator of endocannabinoid signaling pathways . Has a strong preference for very-long-chain lipid substrates; substrate specificity is likely due to improved catalysis and not improved substrate binding . . |
Accessions | ENST00000576316.5 I3L380 ENST00000339157.10 [Q8N2K0-1] ENST00000671784.1 A0A5F9ZGT4 ENST00000376542.8 [Q8N2K0-2] ENST00000471287.5 ENST00000673121.1 ENST00000672258.1 I3L206 ENST00000673227.1 ENST00000672114.1 A0A5F9ZGZ9 I3L294 A0A5F9ZH49 ENST00000671858.1 A0A5F9ZGW7 ENST00000450393.5 A0A5F9ZHG5 A0A5F9ZHM3 I3L440 ENST00000672358.1 A0A5F9ZHF0 ENST00000672331.1 ENST00000491682.5 ENST00000672406.1 Q5T712 A0A5F9ZHQ8 A0A5F9ZHH2 ENST00000673524.1 ENST00000672596.1 I3L1V0 ENST00000673094.1 ENST00000465694.2 Q8N2K0 A0A5F9ZHE8 A0A5F9ZHQ0 A0A5F9ZH71 ENST00000461204.1 ENST00000672566.1 A0A5F9ZH28 A0A5F9ZHB5 ENST00000672871.1 |