I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 25% ± 5% | |
| glutamatergic neuron | 3 studies | 33% ± 7% | |
| dendritic cell | 3 studies | 19% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 25% ± 5% | |
| glutamatergic neuron | 3 studies | 33% ± 7% | |
| dendritic cell | 3 studies | 19% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 22% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 1233.62 | 21 / 21 | 100% | 32.94 | 504 / 504 |
| kidney | 100% | 1976.15 | 89 / 89 | 100% | 51.85 | 901 / 901 |
| liver | 100% | 1609.30 | 226 / 226 | 100% | 27.83 | 406 / 406 |
| ovary | 100% | 1497.28 | 180 / 180 | 100% | 31.50 | 430 / 430 |
| prostate | 100% | 1743.43 | 245 / 245 | 100% | 65.04 | 502 / 502 |
| thymus | 100% | 1858.60 | 653 / 653 | 100% | 53.10 | 605 / 605 |
| uterus | 100% | 1291.09 | 170 / 170 | 100% | 34.45 | 459 / 459 |
| brain | 100% | 2210.83 | 2641 / 2642 | 100% | 49.41 | 705 / 705 |
| intestine | 100% | 1213.93 | 966 / 966 | 100% | 33.22 | 526 / 527 |
| esophagus | 100% | 963.37 | 1441 / 1445 | 100% | 30.11 | 183 / 183 |
| pancreas | 100% | 940.33 | 327 / 328 | 100% | 26.01 | 178 / 178 |
| breast | 100% | 1167.41 | 459 / 459 | 100% | 40.55 | 1114 / 1118 |
| adrenal gland | 100% | 2364.06 | 258 / 258 | 100% | 45.91 | 229 / 230 |
| stomach | 100% | 1093.62 | 358 / 359 | 100% | 31.40 | 285 / 286 |
| lung | 99% | 986.12 | 571 / 578 | 100% | 33.31 | 1155 / 1155 |
| skin | 100% | 1216.60 | 1806 / 1809 | 98% | 34.55 | 464 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 43.62 | 29 / 29 |
| spleen | 100% | 1684.29 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 36.61 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 24.37 | 1 / 1 |
| adipose | 100% | 1073.13 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1017.63 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| heart | 100% | 1402.00 | 857 / 861 | 0% | 0 | 0 / 0 |
| muscle | 96% | 758.87 | 774 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 86% | 13.87 | 69 / 80 |
| peripheral blood | 71% | 750.97 | 660 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0019391 | Biological process | glucuronoside catabolic process |
| GO_0052695 | Biological process | cellular glucuronidation |
| GO_0002084 | Biological process | protein depalmitoylation |
| GO_0005829 | Cellular component | cytosol |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0102390 | Molecular function | mycophenolic acid acyl-glucuronide esterase activity |
| GO_0004553 | Molecular function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO_0008474 | Molecular function | palmitoyl-(protein) hydrolase activity |
| Gene name | ABHD10 |
| Protein name | Palmitoyl-protein thioesterase ABHD10, mitochondrial (EC 3.1.2.22) (Acyl-protein thioesterase ABHD10) (Alpha/beta hydrolase domain-containing protein 10) (Abhydrolase domain-containing protein 10) (Mycophenolic acid acyl-glucuronide esterase, mitochondrial) (EC 3.1.1.93) Abhydrolase domain containing 10, depalmitoylase |
| Synonyms | |
| Description | FUNCTION: Acts as an acyl-protein thioesterase that hydrolyzes fatty acids from acylated residues in proteins . Regulates the mitochondrial S-depalmitoylation of the nucleophilic active site residue of peroxiredoxin-5/PRDX5, a key antioxidant protein, therefore modulating mitochondrial antioxidant ability . Also catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, an active metabolite of the immunosuppressant drug mycophenolate . . |
| Accessions | F8WBJ5 F8WBQ6 ENST00000493784.1 ENST00000494817.1 [Q9NUJ1-3] ENST00000273359.8 [Q9NUJ1-1] ENST00000491580.1 Q9NUJ1 |
