ABCC10 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	3 studies	33% ± 11%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	23% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	2363.57	21 / 21	100%	15.54	504 / 504
esophagus	100%	1884.97	1445 / 1445	100%	20.32	183 / 183
skin	100%	1713.71	1807 / 1809	100%	16.73	472 / 472
intestine	100%	2038.52	966 / 966	100%	16.52	526 / 527
stomach	100%	1526.77	359 / 359	100%	16.02	285 / 286
breast	100%	1624.53	459 / 459	100%	10.78	1113 / 1118
lung	100%	1867.96	577 / 578	99%	15.81	1148 / 1155
pancreas	100%	1634.75	328 / 328	99%	12.40	176 / 178
thymus	100%	2445.04	653 / 653	99%	11.62	598 / 605
adrenal gland	100%	2279.22	258 / 258	99%	10.76	227 / 230
uterus	100%	2547.92	170 / 170	98%	12.89	452 / 459
prostate	100%	2905.50	245 / 245	98%	9.10	494 / 502
ovary	100%	2896.64	180 / 180	97%	11.32	419 / 430
brain	98%	1646.93	2591 / 2642	99%	9.94	700 / 705
kidney	100%	1666.53	89 / 89	91%	7.31	817 / 901
liver	98%	685.65	221 / 226	73%	5.36	298 / 406
eye	0%	0	0 / 0	100%	14.38	80 / 80
spleen	100%	2171.13	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	12.81	45 / 45
ureter	0%	0	0 / 0	100%	14.27	1 / 1
adipose	100%	1415.94	1203 / 1204	0%	0	0 / 0
blood vessel	100%	1492.61	1332 / 1335	0%	0	0 / 0
heart	97%	994.88	834 / 861	0%	0	0 / 0
muscle	97%	762.45	776 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	10.70	28 / 29
peripheral blood	95%	1122.39	881 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0042908	Biological process	xenobiotic transport
GO_0006691	Biological process	leukotriene metabolic process
GO_0071716	Biological process	leukotriene transport
GO_0098656	Biological process	monoatomic anion transmembrane transport
GO_0055085	Biological process	transmembrane transport
GO_0006869	Biological process	lipid transport
GO_0016323	Cellular component	basolateral plasma membrane
GO_0005765	Cellular component	lysosomal membrane
GO_0016020	Cellular component	membrane
GO_0005886	Cellular component	plasma membrane
GO_0009925	Cellular component	basal plasma membrane
GO_0008559	Molecular function	ABC-type xenobiotic transporter activity
GO_0015431	Molecular function	ABC-type glutathione S-conjugate transporter activity
GO_0042626	Molecular function	ATPase-coupled transmembrane transporter activity
GO_0140359	Molecular function	ABC-type transporter activity
GO_0043225	Molecular function	ATPase-coupled inorganic anion transmembrane transporter activity
GO_0016887	Molecular function	ATP hydrolysis activity
GO_0005524	Molecular function	ATP binding

Gene name	ABCC10
Protein name	ATP binding cassette subfamily C member 10 ATP-binding cassette sub-family C member 10 (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 7)
Synonyms	MRP7 SIMRP7
Description	FUNCTION: ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates such as estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4) . May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier (Probable). Mediates multidrug resistance (MDR) in cancer cells by preventing the intracellular accumulation of certain antitumor drugs, such as, docetaxel and paclitaxel . Does not transport glycocholic acid, taurocholic acid, MTX, folic acid, cAMP, or cGMP . .
Accessions	H0Y904 ENST00000244533.7 [Q5T3U5-2] D6R9B3 ENST00000372515.8 Q5T3U5 ENST00000505344.1 ENST00000372530.9 [Q5T3U5-1]

ABCC10 report