Insufficient scRNA-seq data for expression of A4GNT at single-cell level.
Insufficient scRNA-seq data for expression of A4GNT at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 162.17 | 328 / 328 | 63% | 7.61 | 113 / 178 |
kidney | 90% | 72.37 | 80 / 89 | 46% | 1.64 | 417 / 901 |
stomach | 92% | 284.93 | 329 / 359 | 31% | 7.69 | 90 / 286 |
lung | 88% | 19.44 | 507 / 578 | 10% | 1.19 | 119 / 1155 |
bladder | 95% | 17.10 | 20 / 21 | 2% | 0.03 | 8 / 504 |
esophagus | 63% | 8.19 | 905 / 1445 | 26% | 5.10 | 48 / 183 |
thymus | 87% | 20.26 | 571 / 653 | 0% | 0.01 | 2 / 605 |
liver | 67% | 6.53 | 152 / 226 | 15% | 1.08 | 61 / 406 |
uterus | 81% | 12.16 | 138 / 170 | 1% | 0.01 | 4 / 459 |
skin | 78% | 17.59 | 1420 / 1809 | 1% | 0.02 | 6 / 472 |
ovary | 78% | 13.85 | 141 / 180 | 1% | 0.02 | 4 / 430 |
adipose | 73% | 12.03 | 883 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 71% | 10.09 | 948 / 1335 | 0% | 0 | 0 / 0 |
prostate | 71% | 9.60 | 173 / 245 | 0% | 0.00 | 1 / 502 |
intestine | 57% | 9.62 | 552 / 966 | 13% | 2.01 | 67 / 527 |
breast | 65% | 8.78 | 300 / 459 | 1% | 0.01 | 8 / 1118 |
spleen | 61% | 8.72 | 148 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 45% | 3.65 | 115 / 258 | 0% | 0 | 0 / 230 |
brain | 41% | 4.02 | 1092 / 2642 | 0% | 0.01 | 2 / 705 |
heart | 37% | 3.22 | 317 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 13% | 0.82 | 117 / 929 | 0% | 0 | 0 / 0 |
muscle | 11% | 0.63 | 87 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050673 | Biological process | epithelial cell proliferation |
GO_0005975 | Biological process | carbohydrate metabolic process |
GO_0016266 | Biological process | O-glycan processing |
GO_0006493 | Biological process | protein O-linked glycosylation |
GO_0009101 | Biological process | glycoprotein biosynthetic process |
GO_0050680 | Biological process | negative regulation of epithelial cell proliferation |
GO_0000139 | Cellular component | Golgi membrane |
GO_0016020 | Cellular component | membrane |
GO_0008375 | Molecular function | acetylglucosaminyltransferase activity |
Gene name | A4GNT |
Protein name | Alpha-1,4-N-acetylglucosaminyltransferase (Alpha4GnT) (EC 2.4.1.-) |
Synonyms | |
Description | FUNCTION: Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans . Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct . May protect against inflammation-associated gastric adenocarcinomas (By similarity). . |
Accessions | Q9UNA3 ENST00000236709.4 |