A3GALT2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of A3GALT2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of A3GALT2 at tissue level.

III. Associated gene sets

GO_0005975Biological processcarbohydrate metabolic process
GO_0030259Biological processlipid glycosylation
GO_0006688Biological processglycosphingolipid biosynthetic process
GO_0032580Cellular componentGolgi cisterna membrane
GO_0005794Cellular componentGolgi apparatus
GO_0031982Cellular componentvesicle
GO_0047276Molecular functionN-acetyllactosaminide 3-alpha-galactosyltransferase activity
GO_0016757Molecular functionglycosyltransferase activity
GO_0046872Molecular functionmetal ion binding
GO_0001962Molecular functionalpha-1,3-galactosyltransferase activity

IV. Literature review

[source]
Gene nameA3GALT2
Protein nameAlpha-1,3-galactosyltransferase 2 (EC 2.4.1.87) (Isoglobotriaosylceramide synthase) (iGb3 synthase) (iGb3S)
SynonymsA3GALT2P
IGBS3S
DescriptionFUNCTION: Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures. .

AccessionsU3KPV4
ENST00000442999.3