DNA-3-methylguanine glycosylase activity

I. Literature review

[source]
NameDNA-3-methylguanine glycosylase activity
IDGO_0052822
collection_id

Molecular function

Description

Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site.

Related synonym

3-methylguanine DNA glycosylase I, DNA glycosidase I activity, deoxyribonucleate 3-methylguanine glycosidase I

External URL
Genes