glyoxalase III activity

I. Literature review

[source]
Nameglyoxalase III activity
IDGO_0019172
collection_id

Molecular function

Exact synonym

(R)-lactate hydro-lyase, D-lactate dehydratase

Description

Catalysis of the reaction: methylglyoxal + H2O = D-lactate.

Related synonym

glutathione-independent glyoxalase activity

Comment

Note that this term was reinstated from obsolete. Also note that this enzymatic activity converts methylglyoxal to D-lactate in a single glutathione (GSH)-independent step. The other known route for this conversion is the two-step GSH-dependent pathway catalyzed by EC:4.4.1.5 (lactoylglutathione lyase) and EC:3.1.2.6 (hydroxyacylglutathione hydrolase).

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