GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity

I. Literature review

[source]
NameGDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity
IDGO_0004378
collection_id

Molecular function

Exact synonym

GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity

Description

Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage.

Related synonym

GDP-mannose-oligosaccharide-lipid mannosyltransferase II, GDP-mannose:glycolipid 1,3-alpha-D-mannosyltransferase activity, glycolipid 3-alpha-mannosyltransferase activity, guanosine diphosphomannose-oligosaccharide-lipid II mannosyltransferase activity, mannosyltransferase II activity

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Genes