alkylbase DNA N-glycosylase activity

I. Literature review

[source]
Namealkylbase DNA N-glycosylase activity
IDGO_0003905
collection_id

Molecular function

Alternative ID

GO:0004036

Exact synonym

DNA-3-methyladenine glycosidase II activity, alkylbase DNA glycosidase activity

Description

Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.

Related synonym

3-methyladenine DNA glycosylase II, AlkA, DNA glycosidase II activity, DNA-3-methyladenine glycosylase II, deoxyribonucleate 3-methyladenine glycosidase II

External URL
Genes